Signs of a buspirone overdose include vomiting, sweating, stomach discomfort, and oversedation.
If you think someone is overdosing on buspirone, call 911 immediately.
Buspirone is a prescription anti-anxiety medication that is used to treat panic and anxiety disorders, according to the U.S. National Library of Medicine. It is different than other anti-anxiety medications in that it is not a benzodiazepine.
While buspirone has a relatively low potential for abuse, some people do misuse the drug in an attempt to amplify the anti-anxiety effects of the medication. This can cause severe problems and could be very dangerous.
Prescription drug misuse is a widespread problem, with nearly 18 million people misusing prescription medications in 2017, according to the National Institute on Drug Abuse.
Yes, you can overdose on buspirone.
Buspirone is a safe and effective treatment for anxiety when used as directed and taken as prescribed, but using buspirone in ways other than intended can result in a potentially fatal overdose.
Buspirone is not one of the most commonly referenced drugs in drug overdoses, but it could still pose a danger when other risk factors are present.
Some of the risk factors that could potentially trigger a buspirone overdose are:
Taking medication in any way other than as directed is considered prescription drug misuse. You can overdose on buspirone if you take more than the prescribed dosage or if you take it more frequently than prescribed.
If you take the medication in alternative ways, such as snorting, smoking, or injecting it, this increases the risk of overdose.
Using buspirone with other prescribed medications or illicit drugs increases the chances of overdose and dangerous drug interactions.
Drinking while taking anti-anxiety medications can be dangerous. Alcohol is a central nervous system depressant, and this combination can cause dangerous drops in respiratory rates. Mixing alcohol with prescription medications also raises the risk of an overdose.
According to the National Institute on Alcohol Abuse and Alcoholism, mixing buspirone with alcohol could cause the following:
These effects may also be seen in multidrug combinations that include other depressant substances, such as benzodiazepines or opioids. When more than one drug acts as a depressant in the body, slowing down the heart rate and breathing rate, the effects of both drugs are amplified. This is why the combination of buspirone with alcohol and other central nervous system depressants can be so dangerous.
The National Institute on Drug Abuse states that central nervous system (CNS) depressants can cause overdoses by causing the breathing rate to slow down so much that it stops. The results are reduced oxygen to the brain, causing damage to the nervous system, coma, and sometimes permanent brain damage. If medical attention is not provided to begin breathing again, this can result in death.
Mixing buspirone with other substances, especially CNS depressants, is a practice that should be avoided.
Buspirone overdoses can look like overdoses of other substances. They may include a variety of symptoms based on whether the person took buspirone alone or in combination with other substances.
Anyone who experiences any of these symptoms after taking buspirone should receive emergency assistance as soon as possible.
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The quicker a person receives medical care in the case of an overdose, the more likely it is that medical staff will be able to reverse the effects and save the person’s life. More than 70,000 people died in 2017 due to drug overdoses. An overdose is a highly dangerous situation that requires emergency attention.
Buspirone can be safe when taken as directed, but as with all prescription medications, it can quickly become dangerous when not used as intended. Prescription drug interactions can amplify the effects of all substances involved and sometimes cause unpredictable side effects.
Stay safe by following all instructions that come with your medications and do not drink while taking prescription drugs.
(January 2019). Buspirone. U.S. National Library of Medicine. Retrieved February 2019 from from https://medlineplus.gov/druginfo/meds/a688005.html
(2014). Harmful Interactions. National Institute on Alcohol Abuse and Alcoholism. Retrieved February 2019 from from https://pubs.niaaa.nih.gov/publications/Medicine/medicine.htm
(December 2018). What is the scope of prescription drug misuse? National Institute on Drug Abuse. Retrieved February 2019 from from https://www.drugabuse.gov/publications/research-reports/misuse-prescription-drugs/what-scope-prescription-drug-misuse
(January 2019). Overdose Death Rates. National Institute on Drug Abuse. Retrieved February 2019 from from https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates
Poison Control Helpline. Poison Help. Retrieved February 2019 from from https://www.poisonhelp.org/help
(March 2018). Prescription CNS Depressants. National Institute on Drug Abuse. Retrieved February 2019 from from https://www.drugabuse.gov/publications/drugfacts/prescription-cns-depressants